Research group of professor Ermolenko Yu.

Department of Radiochemistry

Radioactive isotopes and chemical sensors for biomedical research

Team

The contact person

Ermolenko Yuri Evgenievich, Doctor of chemical sciences, Professor of the radiochemistry department
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Requirements for the student

Student performance, collaborative experience in a team, knowledge of a foreign language at a level sufficient for reading scientific literature.

Research topics

  • Radioactive isotopes for studying the mechanisms of ion transport in superionic conductors and chalcogenide glasses;
  • Preparation of Sr-82 / Rb-82 radioisotopes for medical research (experimental work is carried out at PETERSBURG NUCLEAR PHYSICS INSTITUTE);
  • Study of the properties of new membrane materials for chemical sensors based on superionic conductors and chalcogenide glasses;
  • Development of sensory systems for determination of mercury, thallium, lead, copper, cadmium, etc. ions on a single semiconductor chip;
  • Research and Development and creation of sensor systems based on enzymes and metalloporphyrins for biomedical analysis based on nanostructures.

Acquired skills

  • work with radioactive isotopes;
  • measurement of ionic and electronic conductivity and diffusion of radioactive isotopes in superionic conductors and chalcogenide glasses;
  • development and creation of new sensor systems;
  • sensory analysis of various analytical media (process solutions, biomedical research, environmental monitoring).

Publications

  1. Koposova, E., Liu, X., Pendin, A., Thiele, B., Shumilova, G., Ermolenko, Y., Offenhäusser, A., Mourzina, Y., Influence of Meso-Substitution of the Porphyrin Ring on Enhanced Hydrogen Evolution in a Photochemical System, Journal of Physical Chemistry C, Volume 120, Issue 26, 2016, Pages 13873-13890. Impact Factor: 4.509.
  2. Yu. E. Ermolenko, D. S. Kalyagin, V. V. Eremin, M. A. Myagkova-Romanova, S. A. Krotov, Yu. G. Vlasov, “Chemical Sensors for Determination of Thallium Ions with Membranes Based on TlI–Ag2S–As2S3: Radiotracer, Solid-State, and Analytical Studies”, Russian Journal of Applied Chemistry, 2016, Vol. 89, No. 6, pp. 949−954. Impact Factor: 0.307.
  3. Muratova, I.S., Mikhelson, K.N., Ermolenko, Y.E., Offenhausser, A., Mourzina, Y., "Chemiresistors based on ultrathin gold nanowires for sensing halides, pyridine and dopamine", Sensors and Actuators, B: Chemical, Volume 232, 2016, Pages 420-427. Impact Factor: 4.758.
  4. Koposova, E.A., Pendin, A.A., Ermolenko, Y.E., Shumilova, G.I., Starikova, A.A., Mourzina, Y.G., Morphological properties and photoconductivity of self-assembled Sn/Co porphyrin nanostructures, Reviews on Advanced Materials Science, Volume 45, Issue 1-2, 2016, pp.15-19. Impact Factor: 1.251.
  5. Muratova, I.S., Mikhelson, K.N. , Ermolenko, Y., Offenhausser, A., Mourzina, Y., "On “resistance overpotential” caused by a potential drop along the ultrathin high aspect ratio gold nanowire electrodes in cyclic voltammetry", Journal of Solid State Electrochemistry, 2016, Pages 1-7. Impact Factor: 2.327.
  6. Elena Yu. Konysheva, Andrey A. Bukaemskiy, Michail V. Kuznetsov, Tianzheng Ma, Yurii E. Ermolenko, "Structural Diversity, Surface Composition, and Redox Behavior in the La0.6Sr0.4CoO3 – PrO2- System" in book “Advances in Chemistry Research. V. 25” J. C. Taylor Ed., ISBN: 978-1-63482-242-8; Nova Science Publishers, 2015; pp.109-130.
  7. Nikolaev, K., Ermakov, S., Ermolenko, Y., Averyaskina, E., Offenhäusser, A., Mourzina, Y., A novel bioelectrochemical interface based on in situ synthesis of gold nanostructures on electrode surfaces and surface activation by Meerwein's salt. A bioelectrochemical sensor for glucose determination, Bioelectrochemistry, Volume 105, October 01, 2015, Pages 34-43. Impact Factor: 3.556.
  8. Liu, X., Stroppa, D.G., Heggen, M., Ermolenko, Y., Offenhäusser, A., Mourzina, Y. Electrochemically induced ostwald ripening in Au/TiO2 nanocomposite, Journal of Physical Chemistry C, Volume 119, Issue 19, 14 May 2015, Pages 10336-10344. Impact Factor: 4.509.
  9. Yuri Ermolenko, Dmtrii Kalyagin, Igor Alekseev, Eugene Bychkov, Vasily Kolodnikov, Natalia Melnikova, Igor Murin,Yuri Vlasov,Yulia Mourzina New membrane material for thallium (I)-selective sensors based on arsenic sulfide glasses // Sensors and Actuators, B: Chemical, Vol. 207, 2015. P. 940-944. Impact Factor: 4.758.
  10. Koposova, E., Shumilova, G., Ermolenko, Y., Kisner, A., Offenhäusser, A., Mourzina, Y. Direct electrochemistry of cyt c and hydrogen peroxide biosensing on oleylamine- and citrate-stabilized gold nanostructures // Sensors and Actuators, B: Chemical,Vol. 207, 2015. P. 1045-1052. Impact Factor: 4.758.
  11. D.S. Kalyagin, Yu.E. Ermolenko, I.E. Alekseev, E.A. Bychkov, S.A. Krotov, N.A. Mel’nikova, I.V. Murin, Yu.G. Vlasov, Ag2S–As2S3–TlI Chalcogenide Glasses as Perspective Material for Solid-State Chemical Sensors // Russian Journal of Applied Chemistry, 2014. — Vol. 87, — № 8. — P. 1044−1048. Impact Factor: 0.307.
  12. Koposova E., Liu, X., Kisner A., Ermolenko Y., Shumilova G., Offenhäusser A., Mourzina Y., «Bioelectrochemical systems with oleylamine-stabilized gold nanostructures and horseradish peroxidase for hydrogen peroxide sensor», Biosensors and Bioelectronics, Volume 57, 15 July 2014, Pages 54-58. Impact Factor: 7.476.
  13. Koposova E., Kisner, A., Shumilova G., Ermolenko Y., Offenhäusser A., Mourzina Y, «Oleylamine-stabilized gold nanostructures for bioelectronic assembly. Direct electrochemistry of cytochrome c», Journal of Physical Chemistry C, Volume 117, Issue 27, 11 July 2013, Pages 13944-13951. Impact Factor: 4.509.
  14. Bokova M., Alekseev I., Kalyagin D., Tsegelnik V., Ermolenko Yu., Bychkov E., «204Tl tracer diffusion and conductivity in thallium thiogermanate glasses», Solid State Ionics, Volume 253, 2013, Pages 101-109. Impact Factor: 2.385.
  15. Ermolenko, Yu.E., Kalyagin, D.S., Subbotina, S.N., Kolodnikov, V.V., Vlasov, Yu.G., «Thallium-selective sensor with a membrane based on Tl4HgI6 ionic conductor», Russian Journal of Applied Chemistry, Volume 86, Issue 2, Pages 192-199, 2013. Impact Factor: 0.307.

Lab equipment

The team has the following scientific equipment: the installation for synthesis of polymeric, crystalline and chalcogenide glass material for membranes chemical sensors, apparatus for investigation of physical-chemical characteristics of the membrane material (ispectrometer Z-2000 precision equipment for measuring resistances and capacitances LCR-78105G), equipment for the diffusion of radioactive isotopes spectrometer Kratos XSAM 800 Mossbauer spectrometer, UV-3600 spectrophotometer Shimadzu) apparatus for studying the analytical characteristics of the sensors, Vacuum laser system for applying thin-film membrane, a complex of computer hardware for data processing multiparameter calibration.

In the works it is planned to use the capabilities of the Resource Center of the St. Petersburg State University, in particular, "X-ray diffraction methods of research" Bruker diffractometer "D2 Phaser", "Methods of substance composition analysis" small-angle X-ray diffractometer SAXS, XRF-1800 X-ray fluorometer, MRC in the direction "Nanotenology "ESXA.

Additionally

Financial supports

  1. "Chemical and biochemical sensor systems: development and investigation of comparative characteristics and mechanisms of operation macro- and nanosensor systems with membranes with different composition". Grant from SPbSU, 12.38.218.2015, 2015-2017.
  2. "Tritium for study the problem of short-lived intermediates. Hermantranilium cations ", RFBR grant 12.15.359.2016, 2016-2018.
  3. "New chemical sensors based on crystalline, glass and bioorganic membranes: ionic and electronic transport at the membrane-solution interface and response mechanisms", RFBR grant "14-03-01079", 2014-2016.
  4. R & D program "START", Development of the composition and method of synthesis of membrane materials for chemical sensors sensitive to thallium, 2013-2014.

Awards, prizes

  • Prize of the St. Petersburg State University, 1st degree for a series of works "Research and development of a new generation of ion-selective electrodes (chemical sensors)."
  • 1st prize of the international publishing house "Nauka" for the best publication in academic journals (Journal of Analytical Chemistry).