Department of Analytical Chemistry
Mass spectrometry research group
Group members
Group Leader Anna GubalPh.D. (Chem.), junior researcher This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Yaroslav DubrovskiiPh.D. (Bio.), researcher This email address is being protected from spambots. You need JavaScript enabled to view it. |
Students and PhD-students
Victoria ChuchinaPhD student |
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Aleksandr KononovPhD student |
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Yegor Lyalkinmaster student |
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Angelina Sorokinabachelor student |
Former members and alumni
Nikolay SolovyevPh.D (Chem.), Assistant lecturer, Department of Life Sciences, School of Science, Institute of Technology Sligo, Ireland |
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Alexandr GaneevProf., Dr. Sci. (Phys.-math.), Institute of Toxicology of Federal Medical-Biological Agency, Lumex Ltd |
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Ilya Gorbunovmaster degree, Analytical chemist of Quality Department JSC BIOCAD |
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Maria Burovabachelor degree |
Collaboration
- A.F.Ioffe Physico-Technical Institute RAS
- N.N. Petrov National Medical Research Center of Oncology of the Ministry of Health of Russia
- Saint Petersburg State Chemical Pharmaceutical University
- Almazov National Medical Research Centre
- Institute of Toxicology of Federal Medical-Biological Agency,
- Lumex Ltd
- Saint-Petersburg Pasteur Institute
- Leibniz Institute for Solid State and Materials Research (IFW), Dresden, Germany
- Shanghai Institute of Ceramics Chinese Academy of Science, Shanghai, China
Research topics
- Inorganic mass spectrometry, elemental, isotopic analysis and depth profiling of solids materials
- Proteomics, metalloproteomics and post-translational protein modification.
- Determination of trace elements in biological substrates and fluids, natural and food objects
- Bioanalytical chemistry, biomarkers
- Determination of volatile organic compounds in air, breath analysis as a tool for the diagnosis of respiratory pathologies
Students are invited to join our team.
Recent publications
2020
- A. Gubal, V. Chuchina, A. Sorokina, N. Solovyev, A. Ganeev, Mass spectrometry-based techniques for direct quantification of high ionization energy elements in solid materials – challenges and perspectives, Mass Spectrom Rev, (2020) doi:10.1002/mas.21643.
- A. Gubal, V. Chuchina, N. Ivanenko, R. Qian, N. Solovyev, A. Ganeev, Microsecond pulsed glow discharge in copper hollow cathode reveals a new approach to ionization and determination of volatile organic compounds, Spectrochimica Acta Part B: Atomic Spectroscopy, (2020) 105986.
- A. Gubal, V. Chuchina, Y. Lyalkin, V. Mikhailovskii, V. Yakobson, N. Solovyev, A. Ganeev, Depth profiling by pulsed glow discharge time-of-flight mass spectrometry with a combined hollow cathode cell, Journal of Analytical Atomic Spectrometry, 35 (2020) 1587-1596.
- V. Chuchina, A. Gubal, Y. Lyalkin, O. Glumov, I. Trefilov, A. Sorokina, S. Savinov, N. Solovyev, A. Ganeev, A study of matrix and admixture elements in fluorine-rich ionic conductors by pulsed glow discharge mass spectrometry, Rapid Commun Mass Sp, 34 (2020) e8786.
- A. Gubal, V. Chuchina, I. Trefilov, O. Glumov, V. Yakobson, A. Titov, N. Solovyev, A. Ganeev, Application of glow discharge mass spectrometry for the monitoring of dopant distribution in optical crystals grown by TSSG method, Crystals, 10 (2020).
- A.D. Titova, V.N. Postnov, S.S. Savinov, N.V. Stolyarova, N.B. Ivanenko, V.A. Chuchina, A.R. Gubal, A.A. Ganeev, Determination of uranium in aqueous solutions by the time-of-flight mass-spectrometry with a pulsed glow discharge after its accumulation on the oxidized carbon nanotubes, Analitika i Kontrol, 24 (2020) 96-106.
2019
- A. Kononov, B. Korotetsky, I. Jahatspanian, A. Gubal, A. Vasiliev, A. Arsenjev, A. Nefedov, A. Barchuk, I. Gorbunov, K. Kozyrev, A. Rassadina, E. Iakovleva, M. Sillanpaa, Z. Safaei, N. Ivanenko, N. Stolyarova, V. Chuchina, A. Ganeev, Online breath analysis using metal oxide semiconductor sensors (electronic nose) for diagnosis of lung cancer, J Breath Res, 14 (2019) 016004.
- Y. Dubrovskii, E. Murashko, O. Chuprina, P. Beltyukov, A. Radilov, N. Solovyev, V. Babakov, Mass spectrometry based proteomic approach for the screening of butyrylcholinesterase adduct formation with organophosphates, Talanta, 197 (2019) 374-382.
- V.V. Abzianidze, S.A. Zakharenkova, N.I. Moiseeva, P.P. Beltyukov, V.A. Polukeev, Y.A. Dubrovskii, V.A. Kuznetsov, Y.G. Trishin, J.E. Mejia, A.A. Holder, Towards lead compounds as anti-cancer agents via new phaeosphaeride A derivatives, Bioorganic and Medicinal Chemistry Letters, 29 (2019) 59-61.
- V.N. Babakov, E.V. Shreiner, O.A. Keltsieva, Y.A. Dubrovskii, V.V. Shilovskikh, I.M. Zorin, N.G. Sukhodolov, I.G. Zenkevich, E.P. Podolskaya, A.A. Selyutin, Application of lanthanum stearate monolayers as a metal-affinity sorbent for the selective sorption of soman adducts to human serum albumin, Talanta, 195 (2019) 728-731.
- I.S. Gorbunov, A.R. Gubal’, A.A. Ganeev, O.V. Rodinkov, L.A. Kartsova, E.A. Bessonova, A.I. Arsen’ev, A.O. Nefedov, L.A. Kraeva, Optimization of the Conditions of Analysis of Exhaled Air by Gas Chromatography–Mass Spectrometry for the Noninvasive Diagnostics of Lung Cancer, J Anal Chem, 74 (2019) 1148-1158.
- A.A. Ganeev, A.I. Drobyshev, A.R. Gubal, N.D. Solovyev, V.A. Chuchina, N.B. Ivanenko, A.S. Kononov, A.D. Titova, I.S. Gorbunov, Hollow Cathode and New Related Analytical Methods, J Anal Chem, 74 (2019) 975-981.
- A. Ganeev, A. Titova, B. Korotetski, A. Gubal, N. Solovyev, A. Vyacheslavov, E. Iakovleva, M. Sillanpää, Direct Quantification of Major and Trace Elements in Geological Samples by Time-of-Flight Mass Spectrometry with a Pulsed Glow Discharge, Anal Lett, 52 (2019) 671-684.
- A. Ganeev, A. Gubal, V. Chuchina, Y. Lyalkin, O. Glumov, V. Yakobson, N. Solovyev, Neon plasma for effective ionisation of oxygen and fluorine in pulsed glow discharge-high ionisation energy elements' quantification in potassium titanyl phosphate single crystals, J Anal At Spectrom, 34 (2019) 588-597.
2018
- A. Gubal, A. Ganeev, N. Solovyev, N. Gubal, B. Korotetski, V. Bodnar, V. Nemets, The formation of an oscillating system during the sputtering of sapphire single crystal with pulsed glow discharge, Solid State Sciences, 83 (2018) 49-55.
- A.A. Ganeev, A.R. Gubal, G.N. Lukyanov, A.I. Arseniev, A.A. Barchuk, I.E. Jahatspanian, I.S. Gorbunov, A.A. Rassadina, V.M. Nemets, A.O. Nefedov, B.A. Korotetsky, N.D. Solovyev, E. Iakovleva, N.B. Ivanenko, A.S. Kononov, M. Sillanpaa, T. Seeger, Analysis of exhaled air for early-stage diagnosis of lung cancer: Opportunities and challenges, Russ Chem Rev, 87 (2018) 904-921.
- A. Gubal, A. Ganeev, V. Bodnar, N. Solovyev, Y. Lyalkin, O. Glumov, V. Yakobson, Direct determination of oxygen and other elements in non-conducting crystal materials by pulsed glow discharge time-of-flight mass spectrometry with potassium titanyl phosphate as an example, Vacuum, 153 (2018) 248-253.
- V. Bodnar, A. Ganeev, A. Gubal, N. Solovyev, O. Glumov, V. Yakobson, I. Murin, Pulsed glow discharge enables direct mass spectrometric measurement of fluorine in crystal materials – fluorine quantification and depth profiling in fluorine doped potassium titanyl phosphate, Spectrochim Acta B, 145 (2018) 20-28.
- N. Solovyev, E. Drobyshev, G. Bjørklund, Y. Dubrovskii, R. Lysiuk, M.P. Rayman, Selenium, selenoprotein P, and Alzheimer's disease: is there a link?, Free Radical Biology and Medicine, 127 (2018) 124-133.
2017
- A. Ganeev, A. Gubal, B. Korotetski, O. Bogdanova, B. Burakov, A. Titova, N. Solovyev, N. Ivanenko, E. Drobyshev, E. Iakovleva, M. Sillanpää, Direct isotope analysis of Chernobyl microparticles using time-of-flight mass spectrometry with pulsed glow discharge, Microchem J, 132 (2017) 286-292.
- A. Gubal, A. Ganeev, V. Hoffmann, M. Voronov, V. Brackmann, S. Oswald, Combined hollow cathode vs. Grimm cell: semiconductive and nonconductive samples, J Anal At Spectrom, 32 (2017) 354-366.
2016
- E. Iakovleva, P. Maydannik, T.V. Ivanova, M. Sillanpää, W.Z. Tang, E. Mäkilä, J. Salonen, A. Gubal, A.A. Ganeev, K. Kamwilaisak, S. Wang, Modified and unmodified low-cost iron-containing solid wastes as adsorbents for efficient removal of As(III) and As(V) from mine water, Journal of Cleaner Production, 133 (2016) 1095-1104.
- A.A. Ganeev, A.R. Gubal, S.V. Potapov, N.N. Agafonova, V.M. Nemets, Mass spectrometric methods for the direct elemental and isotopic analysis of solid materials, Russian Chemical Reviews, 85 (2016) 427-444.
- N.L. Koryagina, E.I. Savel’eva, G.V. Karakashev, V.N. Babakov, Y.A. Dubrovskii, E.S. Ukolova, N.S. Khlebnikova, E.A. Murashko, V.Y. Koneva, A.I. Ukolov, V.A. Kopeikin, A.S. Radilov, Determination of protein adducts of organophosphorus nerve agents in blood plasma, Journal of Analytical Chemistry, 71 (2016) 849-859.
Projects
Group members participated in the following projects (as supervisors or investigators):
Current projects
- Russian Science Foundation (RSF) № 19-73-00135 “Proteomic approach in cultural heritage research” (2019 – present time)
- Russian Foundation for Basic Research (RFBR) № 19-03-00251А “Development of a new approach to online detection of lung cancer markers in exhaled air using pulsed glow discharge mass spectrometry”, (2019 – present time)
- Russian Foundation for Basic Research (RFBR) № 20-015-00498 А “Production of DNA aptamers for interleukin-1 beta by the SELEX method to create nanohybrid structures for medical application” (2020 – present time)
Accomplished projects
- Russian Science Foundation (RSF) № 17-73-20089 “Novel approaches for the analysis of stoichiometry, defect searching and determination of alloying additives in the non-linear crystals, based on the direct mass spectrometric analysis”, (2017- 2020)
- Russian Science Foundation (RSF) № 18-73-00055 “Chemical speciation of selenium and iodine in diabetes mellitus pathology” (2018-2020)
- Research grant of SPSU Alumni Association “Development of express method for the determination of creatinine in urine by DNA-aptamers” (2017 – 2018)