Physical Organic Chemistry

RU

  1. Subrizi A., Amo E.M., Korzhikov-Vlakh V., Tennikova T., Ruponen M., Urtti A. (2019). Design principles of ocular drug delivery systems: importance of drug payload, release rate, and material properties. Drug Discovery Today. 2019. 24(8). 1446-1457. https://doi.org/10.1016/j.drudis.2019.02.001.
  2. Averianov I.V., Stepanova M.A., Gofman I.V., Nikolaeva A.L., Korzhikov-Vlakh V.A., Karttunen M., Korzhikova-Vlakh E.G. Chemical modification of nanocrystalline cellulose for enhanced interfacial compatibility with poly(lactic acid). Mendeleev Communications. 2019. V.29. 220-222. https://doi.org/10.1016/j.mencom.2019.03.036
  3. D.S. Bolotin, V. Korzhikov-Vlakh, E. Sinitsyna, S. N. Yunusova, V. V. Suslonov, A. Shetnev, A. Osipyan, M. Krasavin and V. Y. Kukushkin, Biocompatible zinc(II) 8-(dihydroimidazolyl)quinoline complex and its catalytic application for synthesis of poly(L,L-lactide). Journal of Catalysis. 2019. V.372. 362–369. https://doi.org/10.1016/j.jcat.2019.03.002
  4. I. Pilipenko, V. Korzhikov-Vlakh, V. Sharoyko, N. Zhang, M. Schäfer-Korting, E. Rühl, C. Zoschke, T. Tennikova, pH-Sensitive Chitosan–Heparin Nanoparticles for Effective Delivery of Genetic Drugs into Epithelial Cells, Pharmaceutics. 2019. 11. 317. https://doi.org/10.3390/pharmaceutics11070317
  5. Stepanova, M.; Eremin, A.; Averianov, I.; Gofman, I.; Lavrentieva, A.; Korzhikov-Vlakh, V.; Korzhikova-Vlakh, E. Comparison of Supermacroporous Polyester Matrices Fabricated by Thermally Induced Phase Separation and 3D Printing Techniques. Key Eng. Mater. 2019. 822. 277–283. https://doi.org/10.4028/www.scientific.net/kem.822.277
  6. M. Stepanova, I. Averianov, M. Serdobintsev, I. Gofman, N. Blum, N. Semenova, Y. Nashchekina, T. Vinogradova, V. Korzhikov-Vlakh, M. Karttunen, E. Korzhikova-Vlakh. PGlu-Modified Nanocrystalline Cellulose Improves Mechanical Properties, Biocompatibility, and Mineralization of Polyester-Based Composites. Materials. 2019. V.12. 3435. https://doi.org/10.3390/ma12203435
  7. Kazakova, A.S. Konev, I.M. Zorin, I.S. Poshekhonov, V.A. Korzhikov-Vlakh, A.F. Khlebnikov. PEG-modified aziridines for stereoselective synthesis of water-soluble fulleropyrrolidines. Organic and Biomolecular Chemistry. 2019. V.17. 9864–9873. https://doi.org/10.1039/c9ob01949a
  8. Stepanova M., Averianov I., Solomakha O., Zabolotnykh N., Gofman I., M. Serdobintsev, T. Vinogradova, V. Korzhikov-Vlakh, E. Korzhikova-Vlakh. Composite Biomaterials Based on Poly (L-Lactic Acid) and Functionalized Cellulose Nanocrystals. Journal of Renewable Materials. 2020. 8(4). 383-395. https://doi.org/10.32604/jrm.2020.09206
  9. Ilya S. Kritchenkov, Daniil D. Zhukovsky, Abdelrahman Mohamed, Viktor A. Korzhikov-Vlakh, Tatiana B. Tennikova, Antonina Lavrentieva, Thomas Scheper, Vladimir V. Pavlovskiy, Vitaly V. Porsev, Robert A. Evarestov, Sergey P. Tunik. Functionalized Pt(II) and Ir(III) NIR Emitters and Their Covalent Conjugates with Polymer-Based Nanocarriers. Bioconjug. Chem. 2020. 31. 1327–1343. https://doi.org/10.1021/acs.bioconjchem.0c00020
  10. Korzhikov-Vlakh V., Katernuk I., Pilipenko I., Lavrentieva A., Guryanov I., Sharoyko V., Manshina A.A., Tennikova T.B. Photosensitive Poly-L-lysine/Heparin Interpolyelectrolyte Complexes for Delivery of Genetic Drugs. Polymers 2020. 12. 1077. https://doi.org/10.3390/polym12051077
  11. Pilipenko I.M., Korzhikov-Vlakh V.A., Zakharova N.V., Urtti A., Tennikova T.B. Thermo- and pH-sensitive glycosaminoglycans derivatives obtained by controlled grafting of poly(N-isopropylacrylamide). Carbohydr. Polym. 2020. 248. 116764. https://doi.org/10.1016/j.carbpol.2020.116764
  12. Iudin D., Zashikhina N., Demyanova E., Korzhikov-Vlakh V., Shcherbakova E., Boroznjak R., Tarasenko I., Zakharova N., Lavrentieva A., Skorik Y. and Korzhikova-Vlakh E. Polypeptide Self-Assembled Nanoparticles as Delivery Systems for Polymyxins B and E. Pharmaceutics. 2020. 12. 868. https://doi.org/10.3390/pharmaceutics12090868
  13. Polyakov D., Sinitsyna E., Grudinina N., Antipchik M., Sakhabeev R., Korzhikov-Vlakh V., Shavlovsky M., Korzhikova-Vlakh E., Tennikova T. Polymer Particles Bearing Recombinant LEL CD81 as Trapping Systems for Hepatitis C Virus. Pharmaceutics. 2021. 13. https://doi.org/10.3390/pharmaceutics13050672
  14. Mohamed A., Korzhikov-Vlakh V., Zhang N., Said A., Pilipenko I., Schäfer-Korting M., Zoschke C., Tennikova T. Effect of Poly(L-lysine) and Heparin Coatings on the Surface of Polyester-Based Particles on Prednisolone Release and Biocompatibility. Pharmaceutics. 2021. 13(6). 801. https://doi.org/10.3390/pharmaceutics13060801
  15. Pilipenko I., Korzhikov-Vlakh V., Valtari A., Anufrikov Y., Kalinin S., Ruponen M., Krasavin M., Urtti A., Tennikova T. Mucoadhesive properties of nanogels based on stimuli-sensitive glycosaminoglycan-graft-pNIPAAm copolymers // International Journal of Biological Macromolecules. 2021. Vol. 186. P. 864–872. https://doi.org/10.1016/j.ijbiomac.2021.07.070
  16. Guryanov I., Korzhikov-Vlakh V., Bhattacharya M., Biondi B., Masiero G., Formaggio F., Tennikova T., Urtti A. Conformationally Constrained Peptides with High Affinity to the Vascular Endothelial Growth Factor // Journal of Medicinal Chemistry. 2021. 64. 15. 10900–10907. https://doi.org/10.1021/acs.jmedchem.1c00219
  17. Pilipenko, I.; Korovkina, O.; Gubina, N.; Ekimova, V.; Ishutinova, A.; Korzhikova-Vlakh, E.; Tennikova, T.; Korzhikov-Vlakh, V. Random Copolymers of Lysine and Isoleucine for Efficient mRNA Delivery // International Journal of Molecular Sciences. 2022. 23(10). 5363. https://doi.org/10.3390/ijms23105363
  18. Averianov, I.; Stepanova, M.; Solomakha, O.; Gofman, I.; Serdobintsev, M.; Blum, N.; Kaftuirev, A.; Baulin, I.; Nashchekina, J.; Lavrentieva, A.; et al. 3D-Printed composite scaffolds based on poly(ε-caprolactone) filled with poly(glutamic acid)-modified cellulose nanocrystals for improved bone tissue regeneration // Journal of Biomedical Materials Research Part B: Applied Biomaterials 2022. 110. 2422–2437. https://doi.org/10.1002/jbm.b.35100
  19. Iudin, D.; Vasilieva, M.; Knyazeva, E.; Korzhikov-Vlakh, V.; Demyanova, E.; Lavrentieva, A.; Skorik, Y.; Korzhikova-Vlakh, E. Hybrid Nanoparticles and Composite Hydrogel Systems for Delivery of Peptide Antibiotics. International Journal of Molecular Sciences. 2022. 23(5). 2771. https://doi.org/10.3390/ijms23052771

mh Korjzikov Vlah VA

Head of the Laboratory

Viktor Korzhikov-Vlakh

PhD Chemistry, Associate Professor

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lbt Guryanov IA

Ivan Guryanov

PhD Chemistry, Associate Professor

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mlbh Korjzikova Vlah EG

Evgeniia Korzhikova-Vlakh

PhD Chemistry, Senior Researcher

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mlbh Sinizina ES

Ekaterina Synitsyna

PhD Chemistry, Senior Researcher

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Bauer Viktoriya Aleksandrovna

Viktoriia Bauer

Master student

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Kazak Maksim Konstantinovich

Maxim Kazak

Master student

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Alikparova Elina Renatovna

Elina Alikparova

Bachelor student

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General Fields of Research Projects

  • Development of systems for targeted delivery and controlled release of small biologically active molecules
  • Encapsulation of biopharmaceuticals and their delivery to biological targets
  • Creation of biomimetic scaffolds for tissue engineering

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