Department of Physical Chemistry
Plasmon-enhanced spectroscopy and bioimaging
Short URL for media go.spbu.ru/rgsolovyeva
Group Members
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Group Leader Elena V. SolovyevaPhD, associate professor This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Galina A. Chripunlead engineer This email address is being protected from spambots. You need JavaScript enabled to view it. | This email address is being protected from spambots. You need JavaScript enabled to view it. rooms 2088, 2093 |
Makarova Ksenia Nokodimovnabachelor student laboratory researcher This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Vasilisa O. Svinkomaster student research engineer This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Alisa I. Shevchukmaster student research engineer This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Andrey I. Demenshinmaster student research engineer This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Aleksei A. Smirnovmaster student research engineer This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Simar F. Aslanovbachelor student laboratory researcher This email address is being protected from spambots. You need JavaScript enabled to view it. |
Current Research Topics
| Development of optical labels and theranostics agents for therapeutic photodynamic and hyperthermal therapy based on gold nanoparticles |  |
| Charge transfer processes between photoactive ligand and plasmonic nanoparticle, study of their mechanisms and role in surface-enhanced Raman scattering |  |
| Analytical applications of surface-enhanced Raman spectroscopy |  |
| Development of materials based on hydroxyapatite doped with metal nanoparticles for biomedicine and environmental engineering |  |
| Organic-Inorganic nanocomposites with controlled size and structure for optics and photonics |  |
Collaborations
- Imperial College London, Department of Chemical Engineering, prof. S. Kazarian group
- Sharif University of Technology, Department of Chemistry, prof. Z. Jamshidi group
- Almazov National Medical Research Centre
- Department of Laser Chemistry and Laser Material Science
- Department of Organic Chemistry
Grants, Scholarships and Awards
Grants and Projects
- SPBU Grant «Laboratory of plasmon-enhanced spectroscopy and bioimaging» (within the program «Foundation of Laboratory under leading young scientist leadership») 2022–2024
- RSF Grant 22-73-10052 «Multimodal plasmon tags for bioimaging and therapeutic hyperthermia» 2022-2025
- RFBR Grant 20-33-70034 «Self-organized plasmon structures based on metal nanoparticles and molecular bridges, promising as materials for optics and photonics» 2020–2021
- RSF Grant 17-73-10209 «Development of new organometallic substrates with "hot spots" promising for the use in highly efficient components of nanophotonics»,2017–2019
- Grant SPBU-Sharif University of Technology joint program «Effect of charge transfer in surface-enhanced Raman scattering: experimental and theoretical study» 2020
- Grant from Saint-Petersburg Government «Development of method for express analysis of water-soluble drugs using SERS spectroscopy to quality control» 2020
Students Scholarships and Awards
- Diploma for the best oral presentation at the 6th Russian Conference on Medicinal Chemistry (Vasilisa Svinko, 2024)
- Diploma for the best presentation in the Physics section of the International Conference of Students, Postgraduates and Young Scientists "Lomonosov-2024" (Aleksei A. Smirnov, 2024)
- Diploma for the best oral presentation at the LXXXV conference "Current problems of biomedicine - 2024" (Andrei Demenshin, 2024)
- Diploma for the best oral presentation at the 10th Congress of the Russian Photobiological Society and the conference "Modern Problems of Photobiology" (Alisa Shevchuk, 2023)
- Diploma of 2nd degree for the oral presentation at the XXIX Russian Conference of Young Scientists "Current Problems of Biomedicine - 2023“ (Aleksei A. Smirnov, 2023)
- Grant U.M.N.I.K «Photonics 2022» (Vasilisa Svinko, 2022)
- Youth Prize of Saint-Petersburg for 2021 in the nomination “Science and technology “(Aleksei N. Smirnov, 2021)
Publications
- A.N. Smirnov, A.I. Shevchuk, A.V. Volkova, V.D. Kalganov, E.V. Solovyeva, Gold-silica plasmonic nanobones with tunable size and optical bimodality for bioimaging, Colloids Surfaces A 684 (2024) 133115.
- D.V. Makeeva, V.P. Morgacheva, E.A. Kolobova, E.V. Solovyeva, L.A. Kartsova, Multilayer coatings based on gold nanoparticles and polymers with bovine serum albumin as a functional layer for the chiral separation in capillary electrochromatography, Journal of Separation Science 47 (2024) 2300864.
- Е.В. Соловьева. Спектроскопия гигантского комбинационного рассеяния: 50 лет становления метода и его роль в нанобиотехнологии, Российские Нанотехнологии 19 (2024) 3-19
- A..I. Shevchuk, A. N. Smirnov, V. O. Svinko E. V. Solovyeva Surface-enhanced Raman scattering of sulfo-cyanine NHS esters adsorbed on gold nanoparticles, Russian Journal of General Chemistry (2024) S20-S27
- F. Shamsali, E. Solovyeva, N. Nasiri, Z. Jamshidi, How is the observation of high-order overtones and combinations elucidated by the charge-transfer mechanism in SERS?, Journal of Physical Chemistry A 127 (2023) 10583-10590
- A.I. Shevchuk, V.O. Svinko, A.N. Smirnov, E.V. Solovyeva, SERS study of cyanine dyes: optimization of metal core and molecular label choice for plasmonic nanotags, Dyes and Pigments 216 (2023) 111329
- E.V. Solovyeva, O.V. Odintsova, V.O. Svinko, D.V. Makeeva, D.V. Danilov, Hydroxyapatite-nanosilver composites with plasmonic properties for application in surface-enhanced Raman spectroscopy, Materials Today Communications 35 (2023) 105908
- V.O. Svinko, A.N. Smirnov, A.I. Shevchuk, A.I. Demenshin, A.A. Smirnov, E.V. Solovyeva, Comparative study of fluorescence core-shell nanotags with different morphology of gold core, Colloids and Surfaces B: Biointerfaces 226 (2023) 113306
- A.N. Smirnov, S.F. Aslanov, D.V. Danilov, O.Y. Kurapova, E.V. Solovyeva, One-Pot Synthesis of Silica-Coated Gold Nanostructures Loaded with Cyanine 5.5 for Cell Imaging by SERS Spectroscopy, Nanomaterials 13 (2023) 1267
Conferences
Our group actively participates in scientific conferences, we made more than 10 presentations for 2024, selected ones are indicated below.
- Saratov fall meeting, 23-27 September 2024, Saratov, Russia ( oral, A.I. Demenshin)
- The 31st International conference advanced laser technologies ALT 2024, 23-27 September 2024, Vladivostok, Russia (oral, E.V. Solovyeva)
- XIII International Conference on Chemistry for Young Scientists “Mendeleev 2024”, 2-4 September 2024, Saint-Petersburg, Russia (two posters, S.F. Aslanov, V.O. Svinko)
- 28th International Conference on Raman Spectroscopy – ICORS 2024, 28 July – 02 August 2014, Rome, Italy (oral, E.V. Solovyeva)
- 21st International Conference Laser Optics (ICLO 2024), 1- 5 July, 2024, Saint-Petersburg, Russia (two orals, E.V. Solovyeva and A.I. Demenshin)
- 6th Russian Conference on Medicinal Chemistry "MedChem 2024", 01-04 July 2024, Nizhny Novgorod, Russia (oral, V.O. Svinko)
- XV International Conference "Synthesis and Application of Porphyrins and Their Analogues“, 24-29 июня 2024, Ivanovo, Russia (oral, E.V. Solovyeva)
- The First Russian Conference on Luminescence LUMOS-2024, 23-26 April 2024, Moscow, Russia (oral, E.V. Solovyeva)
- XXXI International Conference of Students, Postgraduates and Young Scientists "Lomonosov-2024", 12-26 April 2024, Moscow, Russia (oral (A.A. Smirnov) and poster (K.N. Makarova))
- LXXXV conference "Current problems of biomedicine - 2024“, 14 April 2024, Saint-Petersburg, Russia (oral, A.I. Demenshin)
Equipment and Methods
Our group has all the necessary resources for multiple step synthesis of nanoparticles and nanomaterials of inorganic and hybrid nature. Laboratory facilities include the equipment :
- Analyzer of nanoparticle concentration NP Counter (based on ultramicroscopy)
- High speed centrifuge Gyrozen 2236R (up to 54111хg), angular rotors 8х50, 12х15, 30*2 mL
- Ultrasonic disperser 950-E (up to 950 W, treated volume of 0.5–600 mL, 1/12, 1/4, 5/12 inch probes)
- Centrifuge MPW-352 (speed up to 18000 rpm, rotors 12×2, 12×7, 6×50 mL)
- Rotary evaporator IKA RV 3 FLEX
- Vacuum drying cabinet SNVS-40/3.5 (temperature up to 350 °С, vacuum up to 1×10−4 mmHg)
- pH-meter Mettler Toledo S-220-Basic with micro and semi-micro pH electrodes
- Ultrasonic bath Sapphire 2.8 TTC
- Analytical balances, magnetic stirrers, pipettes
Our group has a clean area with a complete set of equipment (incubator, laminar flow cabinet, cell counter, centrifuge, plate spectrophotometer, etc.) necessary for cell culture and primary cell tests.
Applied protocols
- Cell viability assay with molecular compounds and nanoobjects
- Detection of reactive oxygen species in solutions and cell samples
- Detection of oxidative stress markers (malondialdehyde, protein carbonyl assay)
- Antioxidant enzymes activity assays (superoxide dismutase, peroxidase, catalase)
- Total antioxidant capacity assays with bioactive compounds and plant extracts (ABTS, DPPH, FRAP)
- Preparation of cell samples for Raman spectroscopy study
- Preparation of cell samples for fluorescence microscopy
Information for students
Научная группа приглашает в лабораторию студентов бакалавриата и магистров 1 года обучения для выполнения курсовых и выпускных квалификационных работ по направлениям:
- Агенты тераностики на основе комплексов гадолиния (III) с производными порфирина
- Исследование фундаментальных закономерностей и развитие прикладных приложений Гигантского комбинационного рассеяния
- Органо-неорганические наноструктуры для фотодинамической терапии
- Гибридные наносистемы для биовизуализации и фототермической терапии
Контактное лицо: доцент Соловьева Е.В., пом. 2088, 2093, This email address is being protected from spambots. You need JavaScript enabled to view it.